Classical Gowers conjecture for random reversible circuits
Determine whether sufficiently deep random reversible circuits form ensembles of cryptographic pseudorandom permutations, so that every efficient observer can distinguish them from uniformly random permutations only with negligible advantage.
References
Despite substantial recent progress on the statistical mixing of random circuits, the computational conjecture still remains wide open as a positive resolution would imply the existence of one-way functions, and hence $\mathsf{P}\neq \mathsf{NP}$.
— On the pseudorandomness of simple quantum processes
(2610.02100 - Dujmovic et al., 1 Oct 2026) in Introduction, Section 1