Adaptive anchoring under unknown or drifting target prevalence
Develop an adaptive prevalence-anchoring mechanism for OLIVE that remains valid when the target prevalence is unknown or drifts over time, rather than relying on the fixed prior ath]ath]\piath] used in the current framework.
References
The one cell that stays open, a prevalence near 5\% with an excess of 1.5, leaves too few declared papers in the simulation to form an anchor, and no quarter the data prefer sits there.
The harder open problem is condition (1): unknown or drifting prevalence needs adaptive anchoring beyond OLIVE's fixed $\pi$; richer hierarchical interfaces would also extend OLIVE's binary posterior to multi-class beliefs, and visually subtle domains such as radiology would swap in a domain-pretrained frozen backbone (e.g., BiomedCLIP).