Papers
Topics
Authors
Recent
Gemini 2.5 Flash
Gemini 2.5 Flash
166 tokens/sec
GPT-4o
7 tokens/sec
Gemini 2.5 Pro Pro
42 tokens/sec
o3 Pro
4 tokens/sec
GPT-4.1 Pro
38 tokens/sec
DeepSeek R1 via Azure Pro
28 tokens/sec
2000 character limit reached

Framework to generate perfusion map from CT and CTA images in patients with acute ischemic stroke: A longitudinal and cross-sectional study (2404.04025v1)

Published 5 Apr 2024 in cs.CV and q-bio.QM

Abstract: Stroke is a leading cause of disability and death. Effective treatment decisions require early and informative vascular imaging. 4D perfusion imaging is ideal but rarely available within the first hour after stroke, whereas plain CT and CTA usually are. Hence, we propose a framework to extract a predicted perfusion map (PPM) derived from CT and CTA images. In all eighteen patients, we found significantly high spatial similarity (with average Spearman's correlation = 0.7893) between our predicted perfusion map (PPM) and the T-max map derived from 4D-CTP. Voxelwise correlations between the PPM and National Institutes of Health Stroke Scale (NIHSS) subscores for L/R hand motor, gaze, and language on a large cohort of 2,110 subjects reliably mapped symptoms to expected infarct locations. Therefore our PPM could serve as an alternative for 4D perfusion imaging, if the latter is unavailable, to investigate blood perfusion in the first hours after hospital admission.

Definition Search Book Streamline Icon: https://streamlinehq.com
References (8)
  1. WHO website, https://www.emro.who.int/health-topics/stroke-cerebrovascular-accident/index.html. Last accessed 5 June 2023
  2. Saver J., Smith E., Fonarow G., Reeves M., Zhao X., Olson D., Schwamm L.: The “Golden Hour” and Acute Brain Ischemia. Journal Stroke 41, 1431–1439 (2010)
  3. SPM12 website, https://www.fil.ion.ucl.ac.uk/spm/software/spm12. Last accessed 5 March 2023
  4. Slicer website, https://https://www.slicer.org/. Last accessed 5 June 2023
  5. VTrails website, https://vtrails.github.io/VTrailsToolkit/. Last accessed 5 June 2023
  6. ITK website, https://itk.org/. Last accessed 5 June 2023
  7. El-Amin M.F: Fractional-Order Modeling of Dynamic Systems with Applications in Optimization, Signal Processing and Control Vol2 Chapter3. 1st edn. Academic Press (Elsevier) (2022)
  8. Stroke National Institute of Health website, https://www.stroke.nih.gov. Last accessed 5 March 2023

Summary

We haven't generated a summary for this paper yet.