Machine learning and multivariate goodness of fit

Abstract: Multivariate goodness-of-fit and two-sample tests are important components of many nuclear and particle physics analyses. While a variety of powerful methods are available if the dimensionality of the feature space is small, such tests rapidly lose power as the dimensionality increases and the data inevitably become sparse. Machine learning classifiers are powerful tools capable of reducing highly multivariate problems into univariate ones, on which commonly used tests such as $\chi^2$ or Kolmogorov-Smirnov may be applied. We explore applying both traditional and machine-learning-based tests to several example problems, and study how the power of each approach depends on the dimensionality. A pedagogical discussion is provided on which types of problems are best suited to using traditional versus machine-learning-based tests, and on the how to properly employ the machine-learning-based approach.