Integrating Large Language Models in Causal Discovery: A Statistical Causal Approach (2402.01454v3)

Abstract: In practical statistical causal discovery (SCD), embedding domain expert knowledge as constraints into the algorithm is significant for creating consistent meaningful causal models, despite the challenges in systematic acquisition of the background knowledge. To overcome these challenges, this paper proposes a novel methodology for causal inference, in which SCD methods and knowledge based causal inference (KBCI) with a LLM are synthesized through ``statistical causal prompting (SCP)'' for LLMs and prior knowledge augmentation for SCD. Experiments have revealed that GPT-4 can cause the output of the LLM-KBCI and the SCD result with prior knowledge from LLM-KBCI to approach the ground truth, and that the SCD result can be further improved, if GPT-4 undergoes SCP. Furthermore, by using an unpublished real-world dataset, we have demonstrated that the background knowledge provided by the LLM can improve SCD on this dataset, even if this dataset has never been included in the training data of the LLM. The proposed approach can thus address challenges such as dataset biases and limitations, illustrating the potential of LLMs to improve data-driven causal inference across diverse scientific domains.

• The paper introduces a novel method integrating LLMs with statistical causal discovery via causal prompting to enhance causal graph accuracy.
• It employs a two-phase approach where initial causal graphs are refined using LLM-derived domain knowledge transformed into a prior knowledge matrix.
• Experiments on benchmark and biased datasets demonstrate that LLM-guided augmentation outperforms standalone causal discovery in statistical validity.

Overview of the Research on Integrating LLMs in Causal Discovery

The paper entitled "Integrating LLMs in Causal Discovery: A Statistical Causal Approach" investigates a novel methodology for enhancing Statistical Causal Discovery (SCD) by integrating LLMs with domain knowledge, specifically through the use of statistical causal prompting techniques. This approach harnesses the strengths of LLMs, such as GPT-4, in processing and interpreting background knowledge to improve causal discovery processes across various datasets.

Key Contributions and Methodology

The authors propose a structured methodology whereby SCD methods and Knowledge-Based Causal Inference (KBCI) facilitated by LLMs are synthesized through Statistical Causal Prompting (SCP). The central premise is that by equipping SCD with background knowledge extracted and interpreted through LLMs, the discovery of causal graphs can more closely align with ground truths, even under data regimes that are observational, biased, or limited in measurement.

Key steps in their methodology include:

1. SCD Execution Without Prior Knowledge: Initial causal discovery is performed on a dataset without any prior input, generating a baseline causal graph.
2. Knowledge Generation and Integration Using LLMs: The results of initial SCD are used to prompt an LLM, like GPT-4, to infer and generate domain-specific causal knowledge, which is quantitatively assessed.
3. Probability-Based Background Knowledge Construction: The insights and knowledge derived from the LLM are transformed into a prior knowledge matrix, serving as an augmentation for the SCD methods in a subsequent discovery phase.

Experimental Validation and Patterns of SCP

The paper validates its methodology through a series of experiments conducted on various datasets including benchmark datasets such as Auto MPG data, DWD climate data, and Sachs protein data. They also include an unpublished and biased health screening dataset to illustrate the method's practical applicability and robustness.

Several patterns of SCP are explored to determine how different types and quantities of statistical information from initial SCD results can influence the performance of both the LLM-based inference and subsequent augmented SCD. The experiments reveal insights into the impact of SCP on enhancing causal accuracy and statistical validity of discovered models, demonstrating that LLM-guided augmentation generally outperforms standalone SCD methods.

Implications and Future Directions

The integration of LLMs in causal inference marks a significant advancement in the quest for precise and interpretable causal models, chiefly by leveraging the immense knowledge repositories within LLMs like GPT-4. The paper’s methodology showcases how modern AI techniques can be harnessed to overcome inherent biases in datasets and enhance the robustness and reliability of causal discovery processes.

Future developments in this domain could explore the integration of more domain-specific LLMs to further specialize and refine causal inference processes. Additionally, expanding the SCP framework to more efficiently handle larger datasets or more complex causal structures, potentially leveraging retrieval-augmented generation techniques, presents promising avenues for research.

This paper’s contributions resonate strongly with ongoing work in integrating AI-driven insights into scientific discovery, pointing toward a future where data-driven and knowledge-driven methods synergize for superior inference and understanding of complex systems.