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Dynamic Graph Enhanced Contrastive Learning for Chest X-ray Report Generation (2303.10323v1)

Published 18 Mar 2023 in cs.CV

Abstract: Automatic radiology reporting has great clinical potential to relieve radiologists from heavy workloads and improve diagnosis interpretation. Recently, researchers have enhanced data-driven neural networks with medical knowledge graphs to eliminate the severe visual and textual bias in this task. The structures of such graphs are exploited by using the clinical dependencies formed by the disease topic tags via general knowledge and usually do not update during the training process. Consequently, the fixed graphs can not guarantee the most appropriate scope of knowledge and limit the effectiveness. To address the limitation, we propose a knowledge graph with Dynamic structure and nodes to facilitate medical report generation with Contrastive Learning, named DCL. In detail, the fundamental structure of our graph is pre-constructed from general knowledge. Then we explore specific knowledge extracted from the retrieved reports to add additional nodes or redefine their relations in a bottom-up manner. Each image feature is integrated with its very own updated graph before being fed into the decoder module for report generation. Finally, this paper introduces Image-Report Contrastive and Image-Report Matching losses to better represent visual features and textual information. Evaluated on IU-Xray and MIMIC-CXR datasets, our DCL outperforms previous state-of-the-art models on these two benchmarks.

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Authors (6)
  1. Mingjie Li (67 papers)
  2. Bingqian Lin (19 papers)
  3. Zicong Chen (4 papers)
  4. Haokun Lin (15 papers)
  5. Xiaodan Liang (318 papers)
  6. Xiaojun Chang (148 papers)
Citations (84)

Summary

Dynamic Graph Enhanced Contrastive Learning for Chest X-ray Report Generation

The research paper titled "Dynamic Graph Enhanced Contrastive Learning for Chest X-ray Report Generation" presents a novel framework for automatic radiology reporting, utilizing dynamic knowledge graphs to address inherent biases in the task. Recognizing the limitations of existing fixed-structure knowledge graphs, the authors propose a dynamic graph structure integrated with contrastive learning paradigms to enhance radiology report generation.

Summary of the Approach

  1. Limitations of Existing Methods:
    • Traditional medical report generation methods suffer from visual and textual bias. This is primarily due to the high similarity between medical images and the repeated occurrence of common sentences describing normal regions.
    • Fixed knowledge graphs used to eliminate biases are not updated during training and therefore may not fully capture the specific knowledge relevant to individual cases.
  2. Proposed Solution:
    • The authors introduce Dynamic Graph Enhanced Contrastive Learning (DCL), which incorporates dynamic graph structures that update per image based on retrieved specific knowledge.
    • This dynamic graph is built upon a pre-constructed general knowledge graph but is augmented with case-specific nodes and relationships derived from semantically similar pre-retrieved radiology reports.
  3. Technical Implementation:
    • Dynamic Graph Construction: Initial structure is based on a knowledge base, enhanced with entities and relations extracted from similar reports using NLP methods like RadGraph.
    • Graph Integration: Use of Transformer-based architectures to propagate information within this dynamically constructed graph. This integration strengthens the nodes' representation by capturing and emphasizing domain-specific knowledge.
    • Contrastive Learning: Utilizes Image-Report Contrastive (IRC) and Image-Report Matching (IRM) losses to refine the model's understanding of semantics across modalities (image and text), improving feature alignment for robust performance enhancements.

Empirical Evaluation

The model was rigorously evaluated on the IU-Xray and MIMIC-CXR datasets, yielding state-of-the-art results in both descriptive accuracy and clinical correctness metrics. Particularly, the DCL approach significantly outperformed existing models in CIDEr and ROUGE-L scores, which are crucial for assessing the relevance and accuracy of generated texts compared to true clinical reports. Furthermore, clinical efficacy metrics were positively impacted, showing improvements in precision, recall, and F1-score — key indicators of the model’s ability to accurately predict medical terminologies.

Implications and Future Work

This work has meaningful implications for the field of automated medical imaging interpretation:

  • Practical Implications: By effectively leveraging both general and specific knowledge, the proposed dynamic approach could potentially alleviate radiologists' workload, supporting accurate diagnosis through automated report generation.
  • Theoretical Contributions: The dynamic integration of knowledge graphs underscores the importance of updating model knowledge contexts in domain-specific applications, opening pathways for more adaptive AI systems in the medical domain.

For future developments, addressing the challenge of knowledge noise introduced by semantically similar but clinically different retrieved reports could further refine the quality of generated outputs. Developing specific objectives or constraints for the dynamic graph construction could mitigate this issue and improve model robustness. Additionally, extending and testing this approach to other modalities and regions beyond chest X-rays could test the scalability and adaptability of this framework across diverse medical imaging scenarios.

In conclusion, the introduction of dynamic knowledge graphs, combined with contrastive learning, presents a substantial advancement in the generation of medical reports, setting a new benchmark in effectively capturing nuanced clinical interpretations from imaging data.