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Lesion Border Detection in Dermoscopy Images Using Ensembles of Thresholding Methods (1312.7345v1)

Published 26 Dec 2013 in cs.CV

Abstract: Dermoscopy is one of the major imaging modalities used in the diagnosis of melanoma and other pigmented skin lesions. Due to the difficulty and subjectivity of human interpretation, automated analysis of dermoscopy images has become an important research area. Border detection is often the first step in this analysis. In many cases, the lesion can be roughly separated from the background skin using a thresholding method applied to the blue channel. However, no single thresholding method appears to be robust enough to successfully handle the wide variety of dermoscopy images encountered in clinical practice. In this paper, we present an automated method for detecting lesion borders in dermoscopy images using ensembles of thresholding methods. Experiments on a difficult set of 90 images demonstrate that the proposed method is robust, fast, and accurate when compared to nine state-of-the-art methods.

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Authors (5)
  1. M. Emre Celebi (25 papers)
  2. Quan Wen (4 papers)
  3. Sae Hwang (1 paper)
  4. Hitoshi Iyatomi (37 papers)
  5. Gerald Schaefer (16 papers)
Citations (205)

Summary

Overview of Lesion Border Detection in Dermoscopy Images Using Ensembles of Thresholding Methods

"Lesion Border Detection in Dermoscopy Images Using Ensembles of Thresholding Methods" presents a novel approach to improving the accuracy and computational efficiency of border detection in dermoscopy images. The authors address a significant challenge in dermatological image analysis—accurately demarcating lesion borders, which is crucial for the early diagnosis of melanoma. The paper proposes the use of an ensemble of thresholding methods that leverages the strengths of various techniques to enhance robustness and accuracy.

Dermoscopy, a critical imaging modality in melanoma detection, can benefit significantly from automation due to the subjective nature of human interpretation. The automated border detection of skin lesions is vital as it informs morphological feature analysis essential for diagnostic accuracy, such as asymmetry and border irregularity. However, the task is complex due to factors like low contrast, irregular borders, and artifacts such as hairs or bubbles.

The Proposed Method

The paper's central innovation is the application of multiple thresholding techniques to the blue channel of dermoscopy images, subsequently fusing these results. By adopting a threshold fusion method within a Markov Random Field framework, the approach achieves pixel-level decision-making that is independent of individual method biases. This fusion exploits the unique characteristics of participating methods for increased resilience against variations in image characteristics.

The primary thresholding methods utilized include Otsu's method, Kittler and Illingworth's approach, Kapur's maximum entropy, and Huang and Wang's fuzzy similarity technique. The selection of these methods is informed by their diverse strengths in threshold determination, which, when combined, offer improved robustness over single-method approaches.

Experimental Validation

The experimental results, evaluated on a set of 90 challenging dermoscopy images, demonstrate that the proposed ensemble method significantly outperforms nine state-of-the-art border detection methods. The presented method yielded a mean XOR error of 8.31%, illustrating not only enhanced accuracy but also reduced variability with a standard deviation of 4.06%. Notably, individual thresholding methods showed higher error rates and greater volatility in performance metrics.

The ensemble thresholding method offers enhanced scalability, executing within 0.1 seconds per image on standard computational hardware, emphasizing its suitability for practical clinical applications without extensive resource demands.

Implications and Future Directions

This research presents a significant contribution to automated dermatological diagnostics by enhancing border detection precision. The ensemble method's strength lies in its adaptive nature, providing consistently accurate results regardless of image variability, a critical factor in clinical settings. Future research could focus on overcoming limitations related to hair and bubble interference, potentially incorporating pre-processing techniques like DullRazor™ for hair removal, and exploring novel methodologies for bubble artifact reduction.

Further development could also involve integrating this ensemble approach with other advanced image analysis methods, such as deep learning, to create comprehensive automated diagnostic systems. Such systems could further enhance early melanoma detection rates and reduce diagnostic inconsistencies caused by human interpretation variance. Overall, this paper lays the groundwork for practical advancements in computer-assisted dermoscopy, with potential expansions into broader image-based diagnostic applications.