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Retrieval Augmented Thought Process for Private Data Handling in Healthcare (2402.07812v2)

Published 12 Feb 2024 in cs.CL, cs.AI, cs.IR, and cs.LG

Abstract: LLMs have demonstrated the strong potential to assist both clinicians and the general public with their extensive medical knowledge. However, their application in healthcare is constrained due to concerns about the privacy of data used in training, which prevents the integration of private and personal information because of security and ethical issues. Moreover, if their capabilities can be enhanced with information retrieval to access up-to-date knowledge, the current integration of LLMs with Information retrieval lacks robustness to imperfect retrieval, which can hinder their effectiveness and even reduce overall performance. In this work, we address this challenge by introducing the Retrieval-Augmented Thought Process (RATP). Given access to external knowledge, RATP formulates the thought generation of LLMs as a multiple-step decision process. To optimise such a thought process, RATP leverages Monte-Carlo Tree Search and learns a proxy reward function that permits cost-efficient inference. On a private dataset of electronic medical records, deliberately excluded from any LLM training set, RATP achieves 35% additional accuracy compared to in-context retrieval-augmented generation for the question-answering task.

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Authors (4)
  1. Thomas Pouplin (5 papers)
  2. Hao Sun (383 papers)
  3. Samuel Holt (18 papers)
  4. Mihaela van der Schaar (321 papers)
Citations (3)

Summary

Retrieval-Augmented Thought Process as Sequential Decision Making

The paper "Retrieval-Augmented Thought Process as Sequential Decision Making" explores the integration of external knowledge into the cognitive processes of LLMs. The aim is to address key challenges, including privacy concerns, hallucination, and context-length limitations, which hinder the broader application of LLMs. The authors propose a novel framework, the Retrieval-Augmented Thought Process (RATP), which conceptualizes thought generation as a sequential decision-making process.

RATP enhances LLMs by allowing them to interact dynamically with external knowledge sources and reason in multiple steps. This approach optimizes thought generation using Monte-Carlo Tree Search (MCTS) and incorporates a Q-value estimator to make cost-effective inferences. The empirical results indicate that RATP delivers a significant performance boost, achieving a 50% improvement in question answering with private data over existing retrieval-augmented models.

Key Components and Methodology

  1. Problem Formalization: The authors frame thought generation as a Markov Decision Process (MDP), using the state space to represent the thought process. The approach leverages decision theory to refine thought sequences systematically through external knowledge access.
  2. Monte-Carlo Tree Search: A critical utility of this methodology is MCTS, which facilitates efficient navigation of the high-dimensional decision space inherent in the thought process. MCTS enables exploration and exploitation of potential decision pathways, significantly enhancing decision-making precision.
  3. Multi-Step Reasoning & Transparency: The paper underscores RATP’s benefits for handling elongated dialogues and complex question-answering tasks that require step-wise thought generation and retrieval capabilities. The integration of an offline Q-learning strategy further extends the efficiency and scalability of this methodology.
  4. Scoring Models: To overcome the lack of real-time feedback, the research includes two scoring models: an offline model-based estimator and a self-critic method. These models serve as proxies for scoring the quality of thought sequences during inference, enabling adaptive learning without direct access to ground truth labels.

Empirical Findings and Implications

The empirical evaluations on datasets BoolQA and emrQA demonstrate RATP’s effectiveness in private domain settings, with RATP showing a 7% accuracy improvement on BoolQA and up to 50% in exact match metrics for emrQA. These enhancements reveal the significant role retrieval-augmented processes can play in domains where data constraints are prevalent.

The paper's implications are twofold:

  • Practical: RATP allows LLMs to better secure privacy-preserving, knowledge-intensive settings by handling data that can't be pre-embedded due to ethical constraints.
  • Theoretical: The framework redefines thought generation in LLMs as a multi-agent, multi-step decision process. This paradigm shift could lead to further research on enhancing the interpretability and grounding of AI models.

Future Directions

Future developments could include refining the model-based scoring systems further and extending RATP’s application to broader contexts where external knowledge is dynamically changing. Additionally, incorporating more nuanced retrieval systems, possibly garnered from continuous learning, might lead to heightened adaptability and effectiveness of LLMs in real-world applications.

In summary, the "Retrieval-Augmented Thought Process as Sequential Decision Making" presents a robust framework for augmenting LLM capabilities, addressing longstanding AI challenges in private data handling, and improving knowledge retrieval efficacy. It is a promising step towards more coherent, adaptable, and secure AI systems.

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