Papers
Topics
Authors
Recent
Gemini 2.5 Flash
Gemini 2.5 Flash
144 tokens/sec
GPT-4o
7 tokens/sec
Gemini 2.5 Pro Pro
46 tokens/sec
o3 Pro
4 tokens/sec
GPT-4.1 Pro
38 tokens/sec
DeepSeek R1 via Azure Pro
28 tokens/sec
2000 character limit reached

Phase Space Analysis of Cardiac Spectra (2306.15425v1)

Published 27 Jun 2023 in physics.med-ph, cs.CL, and cs.CV

Abstract: Cardiac diseases are one of the main reasons of mortality in modern, industrialized societies, and they cause high expenses in public health systems. Therefore, it is important to develop analytical methods to improve cardiac diagnostics. Electric activity of heart was first modeled by using a set of nonlinear differential equations. Latter, variations of cardiac spectra originated from deterministic dynamics are investigated. Analyzing the power spectra of a normal human heart presents His-Purkinje network, possessing a fractal like structure. Phase space trajectories are extracted from the time series graph of ECG. Lower values of fractal dimension, D indicate dynamics that are more coherent. If D has non-integer values greater than two when the system becomes chaotic or strange attractor. Recently, the development of a fast and robust method, which can be applied to multichannel physiologic signals, was reported. This manuscript investigates two different ECG systems produced from normal and abnormal human hearts to introduce an auxiliary phase space method in conjunction with ECG signals for diagnoses of heart diseases. Here, the data for each person includes two signals based on V_4 and modified lead III (MLIII) respectively. Fractal analysis method is employed on the trajectories constructed in phase space, from which the fractal dimension D is obtained using the box counting method. It is observed that, MLIII signals have larger D values than the first signals (V_4), predicting more randomness yet more information. The lowest value of D (1.708) indicates the perfect oscillation of the normal heart and the highest value of D (1.863) presents the randomness of the abnormal heart. Our significant finding is that the phase space picture presents the distribution of the peak heights from the ECG spectra, giving valuable information about heart activities in conjunction with ECG.

Definition Search Book Streamline Icon: https://streamlinehq.com
References (22)
  1. Larry S. Liebovitch. Fractals and chaos simplified for the life sciences. New York: Oxford University Press, 1998.
  2. Balth van der Pol Jun Docts. Sc. and J. van der Mark. Lxxii. the heartbeat considered as a relaxation oscillation, and an electrical model of the heart. Philosophical Magazine Series 1, 6:763–775, 1928.
  3. A mathematical model of automaticity in the sinus node and av junction based on weakly coupled relaxation oscillators. Computers and Biomedical Research, 10(6):529–543, 1977. ISSN 0010-4809. doi:https://doi.org/10.1016/0010-4809(77)90011-8. URL https://www.sciencedirect.com/science/article/pii/0010480977900118.
  4. Nonlinear dynamics of the heartbeat: I. the av junction: Passive conduit or active oscillator? Physica D: Nonlinear Phenomena, 17(2):198–206, 1985. ISSN 0167-2789. doi:https://doi.org/10.1016/0167-2789(85)90004-1. URL https://www.sciencedirect.com/science/article/pii/0167278985900041.
  5. Evidence of chaotic dynamics of brain activity during the sleep cycle. Physics Letters A, 111(3):152–156, 1985. ISSN 0375-9601. doi:https://doi.org/10.1016/0375-9601(85)90444-X. URL https://www.sciencedirect.com/science/article/pii/037596018590444X.
  6. Low-dimensional chaos in an instance of epilepsy. Proceedings of the National Academy of Sciences of the United States of America, 83(10):3513–3517, 1986.
  7. On a mechanism of cardiac electrical stability. the fractal hypothesis. Biophysical journal, 48(3):525–528, 1985. doi:https://doi.org/10.1016/S0006-3495(85)83808-X.
  8. Is the normal heart a periodic oscillator? Biological Cybernetics, 58(3):203–211, 1988. doi:https://doi.org/10.1007/BF00364139.
  9. L’ordre dans le chaos: Vers une approche déterministe de la turbulence. Hermann, 1984.
  10. Measuring the strangeness of strange attractors. Physica D: Nonlinear Phenomena, 9(1):189–208, 1983a.
  11. Estimation of the kolmogorov entropy from a chaotic signal. Physical Review A, 28:2591–2593, 1983b.
  12. Short-term heart rate variability strongly predicts sudden cardiac death in chronic heart failure patients. Circulation, 107(4):565–570, 2003.
  13. Oscillation and chaos in physiological control systems. Science, 197(4300):287–289, 1977.
  14. Pathological conditions resulting from instabilities in physiological control systems. Annals of the New York Academy of Sciences, 316:214–235, 1979.
  15. Is the normal heart rate ”chaotic” due to respiration? Chaos: An Interdisciplinary Journal of Nonlinear Science, 19(2), 2009.
  16. Separation of physiological signals using minimum norm projection operators. IEEE Transactions on Biomedical Engineering, 64(4):904–916, 2017.
  17. Real-time patient-specific ecg classification by 1-d convolutional neural networks. IEEE Transactions on Biomedical Engineering, 63(3):664–675, 2016.
  18. Physiobank, physiotoolkit, and physionet: Components of a new research resource for complex physiologic signals. Circulation, 101(23), 2000.
  19. A fast algorithm to determine fractal dimensions by box counting. Physics Letters A, 141(8):386–390, 1989.
  20. Numerical Analysis. PWS-Kent Pub. Co., Boston, 1993.
  21. Closed form expressions for the finite difference approximations of first and higher derivatives based on taylor series. J. Comp. Appl. Math., 107:179–193, 1999.
  22. Open-loop intermittent feedback control: Practical continuous-time gpc. IEE Proceedings - Control Theory and Applications, 146(5):426–434, 1999.

Summary

We haven't generated a summary for this paper yet.