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Complementary consistency semi-supervised learning for 3D left atrial image segmentation (2210.01438v5)

Published 4 Oct 2022 in eess.IV and cs.CV

Abstract: A network based on complementary consistency training, called CC-Net, has been proposed for semi-supervised left atrium image segmentation. CC-Net efficiently utilizes unlabeled data from the perspective of complementary information to address the problem of limited ability of existing semi-supervised segmentation algorithms to extract information from unlabeled data. The complementary symmetric structure of CC-Net includes a main model and two auxiliary models. The complementary model inter-perturbations between the main and auxiliary models force consistency to form complementary consistency. The complementary information obtained by the two auxiliary models helps the main model to effectively focus on ambiguous areas, while enforcing consistency between the models is advantageous in obtaining decision boundaries with low uncertainty. CC-Net has been validated on two public datasets. In the case of specific proportions of labeled data, compared with current advanced algorithms, CC-Net has the best semi-supervised segmentation performance. Our code is publicly available at https://github.com/Cuthbert-Huang/CC-Net.

Citations (297)

Summary

  • The paper presents CC-Net, an innovative model leveraging complementary consistency between a primary and two auxiliary modules to improve segmentation with minimal labeled data.
  • The method employs cross-training to integrate high-level semantic and high-resolution details for refined decision boundaries in 3D imaging.
  • Experimental validation achieved a Dice score of 89.82% on the LA dataset, outperforming traditional fully-supervised and semi-supervised approaches.

Complementary Consistency Semi-Supervised Learning for 3D Left Atrial Image Segmentation

The paper presents an innovative approach known as CC-Net for semi-supervised segmentation of 3D left atrial (LA) images. The method leverages complementary consistency training to efficiently exploit unlabeled data, which typically poses a challenge to existing semi-supervised segmentation models. The research draws attention to a critical issue in medical image segmentation: the scarcity and high cost of annotated 3D medical images.

Methodological Overview

CC-Net introduces a complementary symmetric structure comprising a primary model and two auxiliary models, aimed at improving the segmentation performance through complementary consistency. The models are designed to exploit complementary information; the main model focuses on extracting high-level semantic information, while the auxiliary models emphasize high-resolution details.

The model implements a cross-training approach where inter-perturbations among the models encourage structural consistency and better decision boundary formulation. This structural setup promises a refined segmentation output, especially in ambiguous areas, by balancing the decision accuracy across the high-resolution and high-level semantic information from the auxiliary models.

Numerical Results

The paper validated the CC-Net on two public datasets, reporting superior segmentation performance when benchmarked against current state-of-the-art methods. On the LA dataset, CC-Net achieved a Dice score of 89.82% using only 10% labeled data for training, demonstrating its ability to capitalize on the availability of large unlabeled datasets while maintaining low numerical uncertainty in the decision boundaries.

When compared to traditional fully-supervised methods like V-Net and other semi-supervised models such as MC-Net+ and DTC, CC-Net consistently provided higher Dice scores and lower Hausdorff Distance and Average Surface Distance metrics. Similar performance trends were observed on the Pancreas-CT dataset, affirming the generalizability of CC-Net across multiple medical imaging tasks.

Implications and Future Directions

The applicability of CC-Net extends beyond LA segmentation; its architecture could be adapted for other domains where labeled data is limited. The implication is significant for fields such as oncology, where timely and accurate organ and lesion segmentation can impact diagnosis and treatment planning.

Theoretical implications underscore the potential of complementary model structures to resolve ambiguities in unlabeled data, enhancing model robustness and prediction accuracy. The idea of complementary consistency stands out as a key innovation, suggesting new pathways for developing semi-supervised learning models.

Looking ahead, potential advancements could involve exploring complementary data-level perturbations to further refine segmentation quality. Moreover, integrating this framework with more diverse datasets could uncover broader application areas and improve the adaptability of semi-supervised learning models in healthcare AI.

In conclusion, this research makes a substantive contribution to the domain of medical image segmentation by introducing a practical and theoretical framework that balances simplicity with innovative semi-supervised learning methodologies. The proposed CC-Net has set a benchmark in leveraging unlabeled data effectively, paving the way for future research in efficient and scalable medical imaging solutions.