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By-passing the Kohn-Sham equations with machine learning (1609.02815v3)

Published 9 Sep 2016 in physics.comp-ph, cs.LG, physics.chem-ph, and stat.ML

Abstract: Last year, at least 30,000 scientific papers used the Kohn-Sham scheme of density functional theory to solve electronic structure problems in a wide variety of scientific fields, ranging from materials science to biochemistry to astrophysics. Machine learning holds the promise of learning the kinetic energy functional via examples, by-passing the need to solve the Kohn-Sham equations. This should yield substantial savings in computer time, allowing either larger systems or longer time-scales to be tackled, but attempts to machine-learn this functional have been limited by the need to find its derivative. The present work overcomes this difficulty by directly learning the density-potential and energy-density maps for test systems and various molecules. Both improved accuracy and lower computational cost with this method are demonstrated by reproducing DFT energies for a range of molecular geometries generated during molecular dynamics simulations. Moreover, the methodology could be applied directly to quantum chemical calculations, allowing construction of density functionals of quantum-chemical accuracy.

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Authors (6)
  1. Felix Brockherde (3 papers)
  2. Leslie Vogt (1 paper)
  3. Li Li (657 papers)
  4. Mark E. Tuckerman (12 papers)
  5. Kieron Burke (90 papers)
  6. Klaus-Robert Müller (167 papers)
Citations (575)

Summary

By-Passing the Kohn-Sham Equations with Machine Learning

The paper "By-passing the Kohn-Sham equations with machine learning" presents an innovative method to improve the efficiency of density functional theory (DFT) calculations by circumventing the traditional Kohn-Sham approach. By employing ML to learn the kinetic energy functional directly from examples, the authors propose a methodology that enables significant computational speed-ups, thereby facilitating the paper of larger systems or extended time scales.

Summary of Key Contributions

Kohn-Sham density functional theory is a cornerstone of electronic structure calculations across disciplines, yet it is computationally intensive due to the necessity to derive the kinetic energy functional's functional derivative. Previous ML approaches to this problem faced limitations in accurately estimating these derivatives. The authors address this by directly learning the density-potential and energy-density maps, bypassing the need for such derivatives.

The paper demonstrates this new ML approach by accurately reproducing DFT energies for diverse molecular configurations obtained from molecular dynamics simulations. This development shows potential for direct applicability to quantum chemical calculations, thereby paving the way for constructing density functionals with quantum-chemical accuracy.

Numerical Results and Claims

The paper provides strong numerical results indicating improved accuracy and reduced computational costs when employing the ML-Hohenberg-Kohn (ML-HK) map approach over typical ML-Obfuscation Free (ML-OF) methods. Notable findings include:

  • The proposed ML-HK approach consistently outperforms ML-OF in accuracy, with lower computational demand.
  • Density errors for complex molecules like benzene and ethane are significantly reduced.
  • The approach successfully predicts energies of configurations captured during molecular dynamics, including challenging scenarios such as proton transfer in malonaldehyde.

Implications and Future Directions

The practical implications of this research are profound for computational physics, chemistry, and materials science. By offering a method to accelerate DFT calculations without compromising accuracy, researchers can explore more complex systems and dynamic processes that were previously computationally prohibitive.

Theoretically, the ML-HK concept represents a meaningful shift in viewing the density-potential mapping as a direct target for ML models. This could influence the future design of functionals, potentially integrating ML-augmented corrections to existing DFT approximations. Moreover, the accuracy of this approach suggests potential developments in constructing nearly exact density functionals tailored to quantum systems.

The direction forward includes extending this methodology to a broader class of molecules and exploring the incorporation of different electronic structure methods into the ML framework. The potential to utilize high-fidelity quantum chemical data for training could lead to functionals with improved performance across diverse molecular and material systems.

Ultimately, this work opens avenues for integrating machine learning techniques into theoretical and computational models, promoting novel research across various scientific domains.