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A stochastic field theory for the evolution of quantitative traits in finite populations (2406.10739v2)

Published 15 Jun 2024 in q-bio.PE, cond-mat.stat-mech, math.PR, and physics.bio-ph

Abstract: Infinitely many distinct trait values may arise in populations bearing quantitative traits, and modeling their population dynamics is thus a formidable task. While classical models assume fixed or infinite population size, models in which the total population size fluctuates due to demographic noise in births and deaths can behave qualitatively differently from constant or infinite population models due to density-dependent dynamics. In this paper, I present a stochastic field theory for the eco-evolutionary dynamics of finite populations bearing one-dimensional quantitative traits. I derive stochastic field equations that describe the evolution of population densities, trait frequencies, and the mean value of any trait in the population. These equations recover well-known results such as the replicator-mutator equation, Price equation, and gradient dynamics in the infinite population limit. For finite populations, the equations describe the intricate interplay between natural selection, noise-induced selection, eco-evolutionary feedback, and neutral genetic drift in determining evolutionary trajectories. My work uses ideas from statistical physics, calculus of variations, and SPDEs, providing alternative methods that complement the measure-theoretic martingale approach that is more common in the literature.

Summary

  • The paper introduces a stochastic field theory framework to model the evolution of quantitative traits in finite populations, accounting for selection, drift, and eco-evolutionary dynamics.
  • It employs stochastic partial differential equations (SPDEs) derived from an infinite-dimensional system-size expansion, offering a mathematically tractable alternative to measure-theoretic approaches.
  • Key results include a stochastic Price equation and gradient dynamics incorporating noise-induced trait shifts, providing insights into phenomena like evolutionary branching under finite population conditions.

Overview of "A Stochastic Field Theory for the Evolution of Quantitative Traits in Finite Populations"

Ananda Shikhara Bhat's paper introduces a theoretical framework for understanding the dynamics of quantitative traits in finite populations through a stochastic field theory approach. The paper leverages concepts from statistical physics and calculus of variations to address the complexity of eco-evolutionary dynamics in finite populations, contrasting with traditional deterministic models that often assume infinite or constant population sizes.

Core Concepts and Methodologies

The paper centers on the development of stochastic field equations for evolutionary dynamics, treating the population as a stochastic field of trait distributions. This approach accounts for natural selection, noise-induced selection, eco-evolutionary interactions, and neutral genetic drift within a finite population context. The stochastic partial differential equations (SPDEs) derived within this framework circumvent some of the mathematical complexities found in measure-theoretic approaches and provide intuitive insights into population dynamics akin to particle systems in statistical physics.

Key Constructs:

  • Stochastic Field Definition: Individuals in a population are modeled as Dirac delta functions over a continuous trait space, allowing the formulation of a 'stochastic field' representing the population state.
  • Birth and Death Rate Functional Forms: The paper defines stochastic processes in terms of birth and death rate functionals dependent on the trait value and population state, with rates incorporating both ecological and mutational dynamics.
  • Infinite-Dimensional System-Size Expansion: To transform the initially discrete jump processes into a continuous form, the paper employs an infinite-dimensional extension of the system-size expansion, leading to functional Fokker-Planck equations and their corresponding SPDEs.
  • Framework Application: The approach yields general SPDEs for population density and trait-frequency fields, alongside deterministic limits recovering known evolutionary equations like the replicator-mutator equations in infinite populations.

Results and Implications

The derived SPDEs offer a sophisticated description of evolutionary dynamics, capturing interactions between deterministic selection pressures and stochastic variations unique to finite populations. Noteworthy outcomes include:

  • Stochastic Price Equation: Provides a probabilistic extension to traditional Price equations, accounting for finite population effects like noise-induced selection, where turnover rates influence evolutionary trajectories.
  • Gradient Dynamics: An SDE for trait means incorporates noise-induced shifts, diverging from classic adaptive dynamics by introducing stochastic corrections due to population fluctuations.

Theoretical Insights and Practical Implications:

  • The framework expands on classical population genetics by incorporating continuous trait distributions and demographic stochasticity.
  • It predicts qualitative behaviors in response to noise, helping elucidate phenomena like evolutionary branching and sympatric speciation under finite conditions.
  • These models are adaptable for investigating the impact of genetic drift and noise-induced selection across various biological systems.

Future Directions

The paper opens avenues for leveraging stochastic and field-theory techniques from theoretical physics in evolutionary biology. Future exploration might focus on refining these models under conditions with multiple interacting traits or spatially structured populations. Furthermore, the efficacy of stochastic field theory in predicting real-world evolutionary patterns presents a compelling question for empirical validation.

Conclusion

Bhat's contribution lies in presenting an alternative, mathematically tractable approach to understanding eco-evolutionary dynamics in finite populations. By embracing complexities and variabilities inherent in real-world systems, this work sets a foundation for more nuanced evolutionary models that could bridge gaps in classical theory, paving the way for applications in computational biology and ecological management. Through this stochastic field theoretic lens, it enriches the analytical toolbox available to researchers probing the depths of evolutionary change and stability.

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