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A Generalist Learner for Multifaceted Medical Image Interpretation (2405.07988v1)

Published 13 May 2024 in cs.CV

Abstract: Current medical artificial intelligence systems are often limited to narrow applications, hindering their widespread adoption in clinical practice. To address this limitation, we propose MedVersa, a generalist learner that enables flexible learning and tasking for medical image interpretation. By leveraging a LLM as a learnable orchestrator, MedVersa can learn from both visual and linguistic supervision, support multimodal inputs, and perform real-time task specification. This versatility allows MedVersa to adapt to various clinical scenarios and perform multifaceted medical image analysis. We introduce MedInterp, the largest multimodal dataset to date for medical image interpretation, consisting of over 13 million annotated instances spanning 11 tasks across 3 modalities, to support the development of MedVersa. Our experiments demonstrate that MedVersa achieves state-of-the-art performance in 9 tasks, sometimes outperforming specialist counterparts by over 10%. MedVersa is the first to showcase the viability of multimodal generative medical AI in implementing multimodal outputs, inputs, and dynamic task specification, highlighting its potential as a multifunctional system for comprehensive medical image analysis. This generalist approach to medical image interpretation paves the way for more adaptable and efficient AI-assisted clinical decision-making.

A Generalist Learner for Multifaceted Medical Image Interpretation

Overview of MedVersa

MedVersa tackles the big challenge in medical AI: the narrow focus of existing systems. While many AI solutions excel at specific tasks like identifying chest diseases or classifying skin conditions, their scope is often limited. Enter MedVersa, a versatile AI model designed to perform multiple medical imaging tasks efficiently. By integrating images and natural language (thanks to LLMs, or LLMs), MedVersa promises more flexible and comprehensive medical image analyses.

Key Components of MedVersa

To understand how MedVersa works, let's break down its main components:

  1. Multimodal Input Coordinator:
    • Handles different types of medical images and text.
    • Uses distinct encoders for 2D and 3D images.
  2. LLM-Based Learnable Orchestrator:
    • Acts as the brain of the operation—decides to handle tasks on its own or use other vision models as needed.
  3. Vision Modules:
    • Specialized modules for various image-based tasks like detection and segmentation.

Numerical Results and Achievements

MedVersa isn't just a theory; it shows promising results. Trained on the MedInterp dataset, which consists of over 13 million labeled instances, MedVersa has outperformed specialist AI systems in several areas:

  • Report Generation:
    • Outperformed specialists with a BLEU-4 score of 17.8 compared to 14.2 from MAIRA-1.
    • Surpassed specialists in multiple metrics, often by notable margins.
  • Vision-Centric Tasks:
    • Beat YOLOv5 in anatomical structure detection, with IoU scores exceeding 0.6 in many cases.
    • Excelled in chest pathology detection, outperforming YOLOv5 in 27 out of 33 conditions.
    • Showed competitive or superior performance in segmentation tasks compared to nnUNet and nnSAM.

Practical Implications and Future Prospects

MedVersa's adaptability means it could significantly streamline clinical workflows. Instead of switching between multiple specialized AI tools, medical professionals can rely on one unified system to handle diverse tasks. This could dramatically reduce turnaround times in busy hospital environments, improving patient care.

Looking ahead, the design of MedVersa allows for the easy integration of new vision models and other advancements in medical AI. This means MedVersa isn't just set for today's medical tasks but is also prepared to evolve with future medical imaging technologies.

Discussion on Dataset and Training

MedVersa’s training predominantly involved X-ray images, but also included smaller datasets from dermatology and CT scans. This doesn't undermine its effectiveness but highlights an area for future work. Including a more diverse range of imaging data could further boost generalization.

Funnel Theory and Visualization Supervision

By training on both vision-language and vision-centric tasks, MedVersa develops a nuanced understanding of medical images. This comprehensive training approach enhances its ability to follow spoken or written instructions, making it more versatile than models only trained on one type of task.

Limitations

While MedVersa has showcased significant advancements, it isn't without limitations. Its dependency on data quality and diversity is critical; non-representative datasets could introduce biases in diagnostics. Moreover, the integration of multiple vision and LLMs could affect long-term manageability and scalability, posing future challenges.

Conclusion

MedVersa is a significant step towards the goal of generalized medical AI. By efficiently integrating both visual and linguistic data, it shows potential in performing a wide range of medical imaging tasks with high accuracy. While there's room for improvement, particularly in dataset diversity, MedVersa's current performance marks a noteworthy advancement in the field of medical AI.

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Authors (5)
  1. Hong-Yu Zhou (50 papers)
  2. Subathra Adithan (7 papers)
  3. Julián Nicolás Acosta (1 paper)
  4. Pranav Rajpurkar (69 papers)
  5. Eric J. Topol (2 papers)
Citations (14)
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