Neighbor-Aware Calibration of Segmentation Networks with Penalty-Based Constraints (2401.14487v1)
Abstract: Ensuring reliable confidence scores from deep neural networks is of paramount significance in critical decision-making systems, particularly in real-world domains such as healthcare. Recent literature on calibrating deep segmentation networks has resulted in substantial progress. Nevertheless, these approaches are strongly inspired by the advancements in classification tasks, and thus their uncertainty is usually modeled by leveraging the information of individual pixels, disregarding the local structure of the object of interest. Indeed, only the recent Spatially Varying Label Smoothing (SVLS) approach considers pixel spatial relationships across classes, by softening the pixel label assignments with a discrete spatial Gaussian kernel. In this work, we first present a constrained optimization perspective of SVLS and demonstrate that it enforces an implicit constraint on soft class proportions of surrounding pixels. Furthermore, our analysis shows that SVLS lacks a mechanism to balance the contribution of the constraint with the primary objective, potentially hindering the optimization process. Based on these observations, we propose NACL (Neighbor Aware CaLibration), a principled and simple solution based on equality constraints on the logit values, which enables to control explicitly both the enforced constraint and the weight of the penalty, offering more flexibility. Comprehensive experiments on a wide variety of well-known segmentation benchmarks demonstrate the superior calibration performance of the proposed approach, without affecting its discriminative power. Furthermore, ablation studies empirically show the model agnostic nature of our approach, which can be used to train a wide span of deep segmentation networks.
- The medical segmentation decathlon. Nature communications 13, 4128.
- Advancing the cancer genome atlas glioma mri collections with expert segmentation labels and radiomic features. Scientific data 4, 1–13.
- Identifying the best machine learning algorithms for brain tumor segmentation, progression assessment, and overall survival prediction in the brats challenge. arXiv preprint arXiv:1811.02629 .
- Deep learning techniques for automatic mri cardiac multi-structures segmentation and diagnosis: is the problem solved? IEEE transactions on medical imaging 37, 2514–2525.
- Transunet: Transformers make strong encoders for medical image segmentation. arXiv preprint arXiv:2102.04306 .
- Local temperature scaling for probability calibration, in: Proceedings of the IEEE/CVF International Conference on Computer Vision, pp. 6889–6899.
- Deep ensembles: A loss landscape perspective. arXiv preprint arXiv:1912.02757 .
- Dropout as a bayesian approximation: Representing model uncertainty in deep learning, in: international conference on machine learning, PMLR. pp. 1050–1059.
- On calibration of modern neural networks, in: International conference on machine learning, PMLR. pp. 1321–1330.
- The kits19 challenge data: 300 kidney tumor cases with clinical context, ct semantic segmentations, and surgical outcomes. arXiv preprint arXiv:1904.00445 .
- nnU-Net: a self-configuring method for deep learning-based biomedical image segmentation. Nature methods 18, 203–211.
- Spatially varying label smoothing: Capturing uncertainty from expert annotations, in: International Conference on Information Processing in Medical Imaging, pp. 677–688.
- A bayesian neural net to segment images with uncertainty estimates and good calibration, in: International Conference on Information Processing in Medical Imaging, pp. 3–15.
- Analyzing the quality and challenges of uncertainty estimations for brain tumor segmentation. Frontiers in neuroscience 14, 282.
- Improving Calibration and Out-of-Distribution Detection in Deep Models for Medical Image Segmentation. IEEE Transactions on Artificial Intelligence .
- Constrained deep networks: Lagrangian optimization via log-barrier extensions, in: 2022 30th European Signal Processing Conference (EUSIPCO), IEEE. pp. 962–966.
- Orthogonal ensemble networks for biomedical image segmentation, in: Medical Image Computing and Computer Assisted Intervention–MICCAI 2021, pp. 594–603.
- Focal loss for dense object detection, in: Proceedings of the IEEE international conference on computer vision, pp. 2980–2988.
- The devil is in the margin: Margin-based label smoothing for network calibration, in: Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition, pp. 80–88.
- Class Adaptive Network Calibration, in: Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition, pp. 16070–16079.
- Abdomenct-1k: Is abdominal organ segmentation a solved problem? IEEE Transactions on Pattern Analysis and Machine Intelligence 44, 6695–6714.
- Isles 2015 - a public evaluation benchmark for ischemic stroke lesion segmentation from multispectral mri. Medical Image Analysis 35, 250–269.
- Confidence calibration and predictive uncertainty estimation for deep medical image segmentation. IEEE transactions on medical imaging 39, 3868–3878.
- Mrbrains challenge: online evaluation framework for brain image segmentation in 3t mri scans. Computational intelligence and neuroscience 2015.
- The multimodal brain tumor image segmentation benchmark (brats). IEEE Transactions on Medical Imaging 34, 1993–2024.
- Calibrating deep neural networks using focal loss. Advances in Neural Information Processing Systems 33, 15288–15299.
- When does label smoothing help? Advances in neural information processing systems 32.
- Trust your neighbours: Penalty-based constraints for model calibration, in: International Conference on Medical Image Computing and Computer-Assisted Intervention, pp. 572–581.
- Calibrating segmentation networks with margin-based label smoothing. Medical Image Analysis 87, 102826.
- Obtaining well calibrated probabilities using bayesian binning, in: Twenty-Ninth AAAI Conference on Artificial Intelligence.
- Predicting good probabilities with supervised learning, in: Proceedings of the 22nd international conference on Machine learning, pp. 625–632.
- Attention u-net: Learning where to look for the pancreas, in: Medical Imaging with Deep Learning.
- Can you trust your model’s uncertainty? evaluating predictive uncertainty under dataset shift. Advances in neural information processing systems 32.
- Regularizing neural networks by penalizing confident output distributions, in: International Conference on Learning Representations (ICLR).
- Probabilistic outputs for support vector machines and comparisons to regularized likelihood methods. Advances in large margin classifiers 10, 61–74.
- U-Net: Convolutional Networks for Biomedical Image Segmentation, in: Medical Image Computing and Computer-Assisted Intervention – MICCAI 2015, pp. 234–241.
- Rethinking the inception architecture for computer vision, in: Proceedings of the IEEE conference on computer vision and pattern recognition, pp. 2818–2826.
- Post-hoc uncertainty calibration for domain drift scenarios, in: Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition, pp. 10124–10132.
- Aleatoric uncertainty estimation with test-time augmentation for medical image segmentation with convolutional neural networks. Neurocomputing 338, 34–45.
- Mix-n-match: Ensemble and compositional methods for uncertainty calibration in deep learning, in: International conference on machine learning, PMLR. pp. 11117–11128.
- UNet++: Redesigning Skip Connections to Exploit Multiscale Features in Image Segmentation. IEEE Transactions on Medical Imaging 39, 1856–1867.
- Balamurali Murugesan (23 papers)
- Sukesh Adiga Vasudeva (1 paper)
- Bingyuan Liu (28 papers)
- Hervé Lombaert (30 papers)
- Ismail Ben Ayed (133 papers)
- Jose Dolz (97 papers)