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Machine learning for electronically excited states of molecules (2007.05320v1)

Published 10 Jul 2020 in physics.chem-ph and stat.ML

Abstract: Electronically excited states of molecules are at the heart of photochemistry, photophysics, as well as photobiology and also play a role in material science. Their theoretical description requires highly accurate quantum chemical calculations, which are computationally expensive. In this review, we focus on how machine learning is employed not only to speed up such excited-state simulations but also how this branch of artificial intelligence can be used to advance this exciting research field in all its aspects. Discussed applications of machine learning for excited states include excited-state dynamics simulations, static calculations of absorption spectra, as well as many others. In order to put these studies into context, we discuss the promises and pitfalls of the involved machine learning techniques. Since the latter are mostly based on quantum chemistry calculations, we also provide a short introduction into excited-state electronic structure methods, approaches for nonadiabatic dynamics simulations and describe tricks and problems when using them in machine learning for excited states of molecules.

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Authors (2)
  1. Julia Westermayr (22 papers)
  2. Philipp Marquetand (36 papers)
Citations (233)

Summary

An Overview of "Machine Learning for Electronically Excited States of Molecules"

This paper, authored by Julia Westermayr and Philipp Marquetand, explores the application of ML to the challenges of modeling electronically excited states of molecules. Excited states are pivotal in various fields like photochemistry, photophysics, and material science, yet their accurate computational modeling is notoriously expensive. The paper reviews how ML can significantly accelerate and enhance simulations of excited states by leveraging its predictive power to interpolate between high-cost quantum chemical calculations.

Key Focus Areas

  1. Quantum Chemistry and Machine Learning Integration: The paper explores how ML is utilized across different quantum chemistry methods such as nonadiabatic dynamics simulations, surface hopping, and others. The authors provide an introductory review of the quantum chemistry foundation necessary for understanding excited states, emphasizing the complexity and computational demands of these systems.
  2. Challenges in Describing Excited States: Theoretical modeling of excited states requires handling a wide array of potential energy surfaces (PESs) and couplings, which can be computationally prohibitive. The paper highlights the use of ML to mitigate these challenges by learning from pre-calculated quantum chemical data to accurately predict PESs and related properties, such as nonadiabatic couplings and transition dipole moments.
  3. ML Models and Descriptors: The review encompasses various ML models like neural networks and kernel ridge regression, along with descriptors used to represent molecular structures. The authors discuss the effectiveness of these tools in modeling excited states, drawing attention to the necessity of managing the phase problem inherent in electronic states to provide consistent and physically meaningful ML predictions.
  4. Applications and Prospects: Several applications of ML in excited states, such as simulating photodynamics and enhancing spectroscopic predictions, are examined. The paper speculates on future developments, suggesting that ML might eventually facilitate the modeling of complex systems, currently impractical with conventional methods.

Implications and Future Directions

  • Efficiency in Simulations: ML offers substantial computational savings and the potential to perform simulations over extended time scales, providing insights into molecular dynamics that were previously inaccessible.
  • Transferability: A significant challenge remains in developing transferable ML models that can generalize across different molecular systems and sizes. The paper suggests that future advancements could include the design of universal descriptors and models, enabling broader applicability.
  • Synthesis with Quantum Chemistry: The paper emphasizes the potential of combining ML with quantum chemistry to develop semi-empirical methods that maintain high accuracy while reducing computational cost.

Conclusion

The paper concludes that while ML is not yet a complete replacement for traditional quantum mechanical approaches, it provides a powerful complement that expands the capabilities of molecular modeling, particularly in the context of excited states. Continued improvements in ML methodology and computational strategies are expected to further transform this field, offering promising avenues for research and application in various scientific domains.