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RECOD Titans at ISIC Challenge 2017 (1703.04819v1)

Published 14 Mar 2017 in cs.CV

Abstract: This extended abstract describes the participation of RECOD Titans in parts 1 and 3 of the ISIC Challenge 2017 "Skin Lesion Analysis Towards Melanoma Detection" (ISBI 2017). Although our team has a long experience with melanoma classification, the ISIC Challenge 2017 was the very first time we worked on skin-lesion segmentation. For part 1 (segmentation), our final submission used four of our models: two trained with all 2000 samples, without a validation split, for 250 and for 500 epochs respectively; and other two trained and validated with two different 1600/400 splits, for 220 epochs. Those four models, individually, achieved between 0.780 and 0.783 official validation scores. Our final submission averaged the output of those four models achieved a score of 0.793. For part 3 (classification), the submitted test run as well as our last official validation run were the result from a meta-model that assembled seven base deep-learning models: three based on Inception-V4 trained on our largest dataset; three based on Inception trained on our smallest dataset; and one based on ResNet-101 trained on our smaller dataset. The results of those component models were stacked in a meta-learning layer based on an SVM trained on the validation set of our largest dataset.

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Authors (6)
  1. Afonso Menegola (4 papers)
  2. Julia Tavares (3 papers)
  3. Michel Fornaciali (8 papers)
  4. Lin Tzy Li (3 papers)
  5. Sandra Avila (41 papers)
  6. Eduardo Valle (50 papers)
Citations (111)

Summary

  • The paper demonstrates that using a U-net inspired segmentation model with ensemble tactics improved the Dice coefficient from 0.753 to 0.793.
  • It details the adaptation of CNN architectures, including ResNet-101 and Inception-v4, fine-tuned on diverse datasets to optimize lesion classification.
  • The study emphasizes effective data augmentation and decision-layer enhancements, suggesting future directions for hybrid segmentation-classification approaches.

Insights into the RECOD Titans Participation in ISIC Challenge 2017

This paper extensively documents the efforts of the RECOD Lab team from the University of Campinas, Brazil, in the ISIC Challenge 2017, focusing on two main tasks: lesion segmentation and lesion classification. Given their previous experience in skin lesion classification, the team adapted and refined deep learning techniques primarily centered around convolutional neural networks (CNNs) to tackle these complex dermatological image tasks.

Lesion Segmentation

The team initiated their segmentation efforts with a U-net inspired approach. The U-net architecture was chosen due to its demonstrated efficacy in biomedical image segmentation tasks. The authors used the official ISIC 2017 dataset consisting of 2,000 dermoscopic images for training, choosing not to incorporate additional external data due to potential validation score inconsistencies.

Several key experiments dominated this section:

  • Model Architecture: The segmentation model based partially on VGG-16 utilized convolutional and up-sampling layers without any fully connected layers. A Dice coefficient served effectively as the loss function, leading to a notable official validation score improvement from 0.753 to 0.783.
  • Data Augmentation: Techniques such as image reshaping, rotational transformations, and shifts were explored, although only resizing and dropout layers appeared to optimize performance without additional computational overhead.
  • Ensemble Approach: Averaging outputs from multiple models trained under various conditions provided the highest achieved score of 0.793.

The authors recognized the importance of a collaborative interaction between lesion segmentation and classification, suggesting future research directions where these tasks could mutually benefit from shared insights or techniques.

Lesion Classification

For lesion classification, the focus was on maximizing model accuracy with deep learning models like ResNet-101 and Inception-v4. Efforts in classification faced bottlenecks due to:

  • Training Data: A crucial aspect was the acquisition of diverse datasets to provide the model with extensive examples and overcome typical deep learning data requirements. The semi and deploy datasets included significant volumes of images combining various public sources for optimized training.
  • Model Optimization: An emphasis on fine-tuning pre-trained models on ImageNet for the specific task was maintained, supporting the hypothesis that models excelling in large image recognition tasks could be adapted for specific medical imaging tasks.
  • Computational Power: Significant computational resources were utilized, amalgamated from university installations and international computational clusters to handle the processing demands of large CNNs.

Key Insights and Challenges

  • Data Strategy: An interesting point noted was the effectiveness of smaller subsets of data (semi dataset) which, contrary to initial presumptions, yielded better validation performance for melanoma detection tasks due to biases not immediately evident.
  • Image Augmentation: Augmentation was a pivotal process, as both training and test augmentation significantly boosted performance. Inception models specifically benefited from per-image normalization, evidently suggesting architectural sensitivity and specifics in hyperparameter tuning.
  • Decision Layer Enhancements: It was revealing that meta-learning techniques using stacking and SVMs on probability outputs of trained models showed substantial improvements, highlighting robust ensemble methods in model decision-making processes.

Implications and Future Directions

These results indicate the utility of deep learning in dermatology and potential paths to enhance classification and segmentation accuracies. The intersection of architectural adjustments and strategic data handling can potentially lead to significant advancements in automated medical diagnostics. Future explorations could focus on augmenting classification and segmentation interactivity, as well as refining ensemble strategies for improved clarity in dermatological pathologies. Researchers are encouraged to further delve into hybrid models leveraging segmentation data to inform classifications, potentially creating feedback loops that enhance accuracy and diagnostic reliability in clinical applications.

The efforts put forth in participation in ISIC 2017 demonstrate significant learning points in handling large-scale data-driven medical image challenges, laying groundwork for continued improvement and exploration in AI-powered healthcare solutions.

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