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Medical image denoising using convolutional denoising autoencoders (1608.04667v2)

Published 16 Aug 2016 in cs.CV and stat.ML

Abstract: Image denoising is an important pre-processing step in medical image analysis. Different algorithms have been proposed in past three decades with varying denoising performances. More recently, having outperformed all conventional methods, deep learning based models have shown a great promise. These methods are however limited for requirement of large training sample size and high computational costs. In this paper we show that using small sample size, denoising autoencoders constructed using convolutional layers can be used for efficient denoising of medical images. Heterogeneous images can be combined to boost sample size for increased denoising performance. Simplest of networks can reconstruct images with corruption levels so high that noise and signal are not differentiable to human eye.

Citations (533)

Summary

  • The paper demonstrates that convolutional denoising autoencoders achieve effective noise reduction in medical images even with small datasets.
  • The methodology leverages convolutional layers to capture spatial correlations, outperforming traditional denoising techniques like median filtering.
  • Experimental results using mammogram and dental X-ray databases indicate improved structural similarity and enhanced diagnostic precision.

Medical Image Denoising Using Convolutional Denoising Autoencoders

The paper "Medical Image Denoising Using Convolutional Denoising Autoencoders" by Lovedeep Gondara presents a significant contribution to the field of medical image processing. The paper demonstrates the efficacy of convolutional denoising autoencoders (CDAEs) for denoising medical images, specifically addressing the challenge of small training datasets typical in medical databases.

Overview

The core focus of the paper is the application of convolutional denoising autoencoders in filtering noise from medical images like mammograms and dental X-rays. Medical imaging techniques often suffer from noise due to various factors, such as efforts to minimize radiation exposure. Thus, denoising becomes crucial for accurate image analysis. Traditional methods, including PDE-based models, wavelets, and non-local means, have been extensively utilized. However, recent advancements in deep learning have offered promising alternatives.

Methodology

The paper emphasizes that convolutional layers in autoencoders provide superior denoising capabilities thanks to their adeptness at leveraging spatial correlations in images. A notable claim of the paper is the strong performance of CDAEs despite small sample sizes, which contradicts the common assumption that large datasets are necessary for deep learning models to perform well.

Technical Approach:

  • Autoencoder Configuration: The paper utilizes a straightforward architecture for the CDAE, demonstrating its ability to reconstruct images even with severe noise.
  • Datasets: Two datasets were used—mini-MIAS mammogram database and a dental radiography database. Preprocessing involved reducing image resolution for computational feasibility.
  • Evaluation: The evaluation employed structural similarity index measure (SSIM) instead of PSNR, as it better aligns with human perception of image quality.

Results

The experimental findings indicate that CDAEs outperform conventional methods like median filters, particularly at higher noise levels. The model showed promising results even with sample sizes as small as 300. Increasing the dataset to incorporate heterogeneous sources further slightly improved performance, showcasing the potential for combining different databases to enhance denoising results. The paper also examined performance across varying noise levels and types, affirming the robustness of CDAEs.

Implications

The ability of CDAEs to function effectively with limited training data is particularly valuable in medical contexts, where large annotated datasets are often unavailable. This characteristic could facilitate wider adoption of deep learning models in medical image processing. Furthermore, the improved denoising capabilities can significantly enhance the quality of diagnostic imaging, leading to better patient outcomes.

Future Work

The paper suggests several avenues for future research: optimizing CNN architectures for small datasets, applying these methods to high-resolution images, and experimenting with initial preprocessing methods like SVD and median filters. These directions aim to refine the balance between computational resources and model performance.

In summary, the paper provides a comprehensive exploration of using convolutional denoising autoencoders for medical image denoising, presenting empirical evidence of their viability with small datasets. The findings hold substantial implications for enhancing image quality in medical diagnostics and lay the groundwork for future exploration into more advanced architectures and integration techniques.